Trinov (Brotzu Lotion) – Novice Hair Loss Treatment Reviewed

giuseppe brotzu lotion blocks dht

I don’t know whether you have noticed this, but, as much as people want to treat their hair problems, what keeps them from making the first step is their uncertainty concerning the safety and the authenticity of the treatment procedures.

Quite many hair treatment options have been developed, albeit with different mechanisms of action, like LLLT, micro-needling and different topical solutions.

Recently, Brotzu lotion (also known as Trinov) was produced and released into the market as a potent remedy for hair loss. Since its release, the reviews about it have been very impressive, and its effectiveness is claimed to be worth the cost.

Read on:

What is brotzu lotion?

trinov brotzu lotion package

Since rumors of its development emerged, Trinov has broken the record for being one of the most hyped products for hair loss.

Its initial name was Brotzu lotion, but it has since changed to Trinov. The medication will certainly not cure your hair loss because it doesn’t provide curative value, though it is a very rare and potent remedy for treating hair loss.

What does this even mean?

A curative medication is that medication that entirely eliminates your condition. Trinov doesn’t boast of this property. It can only manage your hair loss as long as you use it. When you stop the therapy, then your hair loss may set in again. But, who engineered this great medication?

Development of Brotzu lotion:

Trinov as a product is patented by the Italian manufacturer – Fidia Farmaceutici. The brain behind the development of this impressive gem of cosmetic industry is one talented octogenarian inventor – Dr. Giovanni Brotzu, from whom the name Brotzu lotion was coined.

At 83 years old, Dr. Giovanni may have just made one of the most significant breakthroughs of his life with the invention of this medication, because it is not very likely that he will contribute to further discoveries considering his advanced age.

Despite being developed by Brotzu, the patent for the medication has been secured by Fidia Farmaceutici instead of the Brotzu family. Fidia is the current owner of the drug and the company currently producing Trinov.

The science behind the working of Trinov

On 14th April 2018, Dr. Brotzu was set to deliver a powerful presentation about the lotion he had developed to a group of enthusiasts who attended the annual conference at the Italian Society for Hair Science and Restoration that year.

The study by Dr. Giovanni was also posted in the National Center for Biotechnology Information (NCBI) website.

Hair loss has been attributed to the hormone dihydrotestosterone. The science behind the mechanism of Trinov is that when you inhibit the formation of dihydrotestosterone (DHT) from testosterone, you will significantly reduce the risk of suffering from hair loss.

How does it work?

The ingredients in Trinov include Dhomo-Gamma-Linoleic acid, S-equol, and Propionyl-l-carnitine. Linoleic acid is an essential precursor of prostaglandin E1 (PGE 1) – a very crucial component in improving the microcirculation in the body and a potent inhibitor of inflammation.

Equal, on the other hand, it works by inhibiting the enzyme 5 alpha-reductase. The blockade of this enzyme prevents the conversion of testosterone into DHT.

hair follicles affected by DHT

The carnitine component of Trinov acts by promoting the metabolism of lipids. This mechanism provides additional energy to the body.

These three key ingredients of Trinov contain a high number of liposomes which ensure that they are effective when administered through the transdermal route. Dihydrotestosterone is known to be the core cause of balding. It is known to make the hair follicles miniaturize making them thin out and possible fall off leading to hair loss.

If you want to stop hair loss properly, you have to block dihydrotestosterone to help reverse the miniaturization process of your hair.

Conveniently, Trinov is among the only medications that actively blocks the formation of dihydrotestosterone. As this medication blocks the enzyme 5 alpha-reductase, it gives the hair follicles an opportunity to produce thicker, fuller and healthier hair.

Brotzu lotion also increases the levels of PGE1 as mentioned previously. The growth of hair can be attributed to prostaglandin E2 and D2, Dr. Giovanni explained that the action of PGE1 on hair growth is similar to that of PGE2.

Most medications for hair loss targets PGE2 while Trinov only focuses on PGE1. In both circumstances, the overall goal is to increase the levels of these prostaglandins so that they can help you develop thicker, stronger and fuller hair.

What are the results for those suffering from hair loss?

The experimental study of Trinov which was published in the year 2014 showed that the medication is beneficial to both women and men with quite some hair loss disorders.

These are the results of a man patient after 6 months of treatment:

trinov brotzu results after 6 months
6 months results. SOURCE:

So, which types of hair loss are effectively managed by Trinov?

Certainly, or so, the mechanisms of this lotion make it preferable for treating androgenic alopecia and alopecia areata.

In androgenic alopecia, the hair follicles are inhibited by DHT which is synthesized by the 5 alpha-reductase. By blocking this enzyme, Trinov actively reverses the loss of hair.

In alopecia areata, hair loss occurs because the immune system mounts an attack on the hair follicles. The inflammatory processes and the damage that ensues is actively managed by prostaglandins E – a key component of Brotzu lotion.

Irrespective of the type of air loss you are suffering from, three things stand out from the studies involving Trinov:

  • this formula is very effective in slowing down (or stopping) hair loss
  • it promotes hair regrowth in scalp areas that have suffered massive alopecia
  • Trinov also strengthens and fortifies your hair

This great news stresses merely on the fact that Brotzu lotion is highly beneficial for both men and women who are suffering from hair loss.

Trinov for men and women

Most men have raised the concern that: will lowering the levels of DHT make you less of a man?

The answer is a resounding No!

Blocking the formation of this hormone doesn’t have anything to do with being a man. Let’s face it: the physiologic changes that make men from boys is majorly under the influence of testosterone and not dihydrotestosterone.

Over the past few years, studies have revealed that dihydrotestosterone is undoubtedly a greater influencer of hair loss than testosterone.

Although both of them are androgens, most effective medications for reversing hair loss block the formation of DHT and not testosterone itself.

Another key concern has always been: why would blocking dihydrotestosterone, a supposed male androgenic hormone, help women with hair loss?

Well, the truth is that women also produce testosterone, though in significantly lower amounts compared to men.

Most people have not always appreciated this fact and only think that testosterone is a male hormone.

In women, the ovaries take the role of producing testosterone. In the presence of the enzyme 5 alpha-reductase, this testosterone is converted into DHT which then potentiates hair loss.

A prospective investigation done on Trinov indicated that applying this medication topically on a daily regimen increased the hair count more significantly in women. On the other hand, the increase in hair count was only slightly marginal in men. This comparison was achieved by the results obtained in 6 months.

woman head before and after trinov
6 months results. SOURCE:

The results also showed that Trinov increased the anagen hair and reduced telogen hair in males within the first three months.

In females, this topical lotion showed quite impressive results. The anagen hair was increased while the telogen hair reduced in just one month.

From the results, Trinov is clearly more effective and fast-acting in women more than men. Nevertheless, it works to produce desirable results in both men and women who are suffering from alopecia.

Significant advantages of Brotzu lotion

There are specific pros of this medication that improves its ease of use and effectiveness. Here are some that you should know:

  • it is available over the counter just like minoxidil,
  • it is widely accessible being that it doesn’t require a prescription like finasteride,
  • you won’t need to visit those expensive hair clinics to get treatment,
  • the application is easy – just like with all lotion products.

Side effects of Brotzu lotion

The direct side effects of Trinov such as allergies have not been reported. But it goes without saying that those who are sensitive to this product or its ingredient can suffer from allergies following any topical administration of Trinov.

Other side effects are due to the inhibition of DHT. Inhibiting this hormone predisposes you to the following:

  • altered/loss of libido
  • reduced ejaculatory volume
  • it may cause problems with achieving and maintaining an erection
  • anxiety
  • weakness
  • depression
  • dizziness

These side effects do not occur in everyone and cannot be experienced all at the same time.

Price of Trinov and where to buy it online

trinoc lotion package with price tag

Trinov is an over the counter medication that can be found in most drug stores – both online and offline. For example, currently, you can buy it from:

  • (worldwide delivery in 48/72 h)

The average price for Trinov ranges between $75 and $80. These are the U.S. dollar estimates of the general pricing in euros which ranges from 67 to 72 euros.

Most sites that sell Trinov are written in Italian which may be somewhat challenging to understand. However, you can use Google translate to convert the page into a language that you know best. This technique is pretty much straight forward.

Besides, there are those companies that will provide shipping services for you at a cost when you buy the product from Europe. As a result, you should include the shipping fee in your budget to ensure that your purchase is smooth.

Bottom line

Trinov is indeed not a miracle drug that will cure your hair loss overnight. The good news is that it will help reverse your hair loss as long as you maintain using it as instructed by the manufacturer. Medications are not always 100% percent effective.

But, as long as you can mask your signs and manage your symptoms, then you will be comfortable. If one method doesn’t restore your hair, do well to consider other treatment options. You can also consult your doctor where necessary.

  • Brotzu, G., Fadda, A. M., Manca, M. L., Manca, T., Marongiu, F., Campisi, M., & Consolaro, F. (2019). A liposome‐based formulation containing equol, dihomo‐γ‐linolenic acid and propionyl‐l‐carnitine to prevent and treat hair loss: A prospective investigation. Dermatologic therapy, 32(1), e12778. DOI:
  • Urysiak-Czubatka, I., Kmieć, M. L., & Broniarczyk-Dyła, G. (2014). Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia. Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii, 31(4), 207. DOI:

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